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Comparison of Interleukin-1β Levels in Gingival Crevicular Fluid and Peri-Implant Crevicular Fluid and Its Relationship with Clinical Indexes
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چکیده: (2462 مشاهده) |
Objective: Interleukin-1 (IL-1 ) is one of the most important cytokines which seems to have an important role in the inflammatory process in gingival and peri-implant tissues. The aim of this split-mouth study was to investigate the relationship between the concentration of IL-1 in gingival crevicular fluid (GCF) and peri-implant crevicular fluid (PICF) and clinical parameters such as plaque index (PI), gingival index (GI), pocket depth (PD) and bone loss (BL).
Materials and Methods: In 32 patients, PICF and GCF samples of 41 implants and 41 contralateral teeth were collected and IL-1 was determined by enzyme-linked immunosorbent assay (ELISA). PI, GI, PD and BL were recorded for each of the samples.
Result :The positive correlation between the level of IL-1 and PI, GI, PD and BL in both groups was observed (P<0.0001). In similar conditions, the level of IL-1 was greatly higher in PICF than GCF (75.26 pg/ and 45.71 pg/ , respectively) (P=0.001).
Conclusion: The findings of the present study indicated that the level of IL-1 may be an important supplement to clinical findings in measuring the health status of gingival or peri-implant tissues.
Source:
Journal of Dentistry of Tehran University of Medical Sciences
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نوع مطالعه: پژوهشي |
موضوع مقاله:
پریودنتولوژی
دریافت: 1391/11/12 | انتشار: 1390/10/25
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