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:: دوره 3، شماره 3 - ( مجموعه مقالات بیماری های دهان 1390 ) ::
جلد 3 شماره 3 صفحات 0-0 برگشت به فهرست نسخه ها
Evaluation of the therapeutic effects of Aloe vera gel on minor recurrent aphthous stomatitis
چکیده:   (2443 مشاهده)

 Background: Aphthous ulcer is one of the most common diseases of the oral cavity with no known effective treatment so far, which could cause severe discomfort in patients. Aloe vera (A.V.) is a tropical plant with anti-inflammatory and immunostimulant effects, which could be of benefit in a diversity of wound healing conditions. The aim of this study is to evaluate topically administered A.V. gel on oral cavity minor aphthous healing.

 Materials and Methods: As a double-blind (case control) clinical trial, 40 patients with oral minor aphthous lesions were randomly allocated in either the case group (A.V. gel) or the control (placebo) group. The healing time (days after gel application), patient’s pain score the lesion and its surrounding inflammation diameters were recorded for 2 weeks. The obtained results were analyzed by either “Fishers exact” or t-student test using SPSS software.

 Results: The mean (±SD) of patients’ age was 29.25 ± 8.48 and 27.95 ± 7.96 years in the control and A.V.-treated groups, respectively, which were not significantly different (P > 0.05). The duration of complete wound healing, pain score, wound size and inflammation zone diameter in the A.V.- treated group were significantly lower than the control group (P ≤ 0.05) on specific time points after treatment.

 Conclusion: It seems likely that A.V. 2% oral gel is not only effective in decreasing the recurrent aphthous stomatitis patients’ pain score and wound size but also decreases the aphthous wound healing period.


 Source: Dental Research Journal

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نوع مطالعه: پژوهشي | موضوع مقاله: بیماری های دهان
دریافت: 1391/9/6 | انتشار: 1390/10/25
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Babaee N, Zabihi E, Mohseni S, Moghadamnia A A. Evaluation of the therapeutic effects of Aloe vera gel on minor recurrent aphthous stomatitis. 3 2012; 3 (3)
URL: http://idai.ir/article-1-726-fa.html

Evaluation of the therapeutic effects of Aloe vera gel on minor recurrent aphthous stomatitis. 1. 1390; 3 (3)

URL: http://idai.ir/article-1-726-fa.html



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Creative Commons License این مقاله تحت شرایط Creative Commons Attribution-NonCommercial 4.0 International License قابل بازنشر است.
دوره 3، شماره 3 - ( مجموعه مقالات بیماری های دهان 1390 ) برگشت به فهرست نسخه ها
جامعه اسلامی دندانپزشکان Islamic Dental Association of IRAN

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