[Home ] [Archive]   [ فارسی ]  
Search in website

Advanced Search
..
:: Volume 2, Issue 2 (1-2012) ::
3 2012, 2(2): 0-0 Back to browse issues page
Biocompatibility of mineral trioxide aggregate and three new endodontic cements: An animal study
Mohammad-Ghasem Aminozarbian , Masoud Barati , Iman Salehi * , Seyed Behrouz Mousavi
Department of Endodontics and Torabinejad Dental Research Center, School of dentistry, Isfahan University of Medical Sciences, Isfahan, Iran
Abstract:   (4352 Views)

 Background: Introducing new endodontic cements should await comprehensive investigations
and new formulations have to be tested in vivo before applying in human beings. So, the purpose
of this study was to compare the biocompatibility of new endodontic cements, calcium aluminate
α-aluminate cement (CAAC), calcium aluminate α-aluminate plus cement (CAAC plus), and a
mixture of wollastonite and CAAC cement (WOLCA) and mineral trioxide aggregate (MTA), in
subcutaneous connective tissue of rats.
Materials and Methods: Twenty-seven Wistar rats were divided into three groups of 7, 14, and
30 experimental days. Sterile polyethylene tubes were filled with MTA, CAAC, CAAC Plus, and
WOLCA cement and implanted subcutaneously. Empty tubes were implanted as negative control.
After the experimental periods, animals were sacrificed by anesthetic overdosing. The occurrence
of inflammatory responses was scored according to the previously established scores. Data were
statistically analyzed using Friedman, Wilcoxon, Kruskal-Wallis, and Mann-Whitney tests. The level
of significance was 5% (P<0.05).
Results: There was a statistically significant difference between experimental and negative control
sites in each group (P<0.05). CAAC Plus showed the highest mean scores of inflammation, compared
with MTA, CAAC, and WOLCA cement sits at the end of all periods (P<0.05). There were no
statistically significant differences between inflammatory scores of each site in different experimental
groups, except CAAC plus sites, in which inflammation increased significantly with time (P<0.05).
Conclusion: According to the results of the current study, biocompatibility of CAAC and WOLCA
cement were comparable with that of MTA, but CAAC Plus induced an inflammatory response
higher than MTA, therefore is not biocompatible.


 Source: Dental Research Journal

 Full text

 

Keywords: Biocompatibility, mineral trioxide aggregate, new endodontic cement, sodium hexametaphosphate
     
Type of Study: Research | Subject: Endodontics
Received: 2012/03/27 | Published: 2012/01/15
Send email to the article author

Add your comments about this article
Your username or Email:

CAPTCHA


XML     Print


Download citation:
BibTeX | RIS | EndNote | Medlars | ProCite | Reference Manager | RefWorks
Send citation to:

Aminozarbian M, Barati M, Salehi I, Mousavi S B. Biocompatibility of mineral trioxide aggregate and three new endodontic cements: An animal study. 3 2012; 2 (2)
URL: http://idai.ir/article-1-400-en.html


Rights and permissions
Creative Commons License This work is licensed under a Creative Commons Attribution-NonCommercial 4.0 International License.
Volume 2, Issue 2 (1-2012) Back to browse issues page
جامعه اسلامی دندانپزشکان Islamic Dental Association of IRAN

کلیه حقوق سایت متعلق به جامعه اسلامی دندانپزشکان ایران است. تماس با ما

Persian site map - English site map - Created in 0.03 seconds with 34 queries by YEKTAWEB 4710