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Nitrogen containing bisphosphonates associated osteonecrosis of the jaws: A review for past 10 year literature
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چکیده: (1411 مشاهده) |
Nitrogen containing bisphosphonate (N-BP) therapy is used extensively to treat osteoporosis
and osteolytic bone lesions. Recently, a special form of osteonecrosis limited to the maxillofacial
skeleton has been discovered especially within those patients who are receiving either long-term
N-BP therapy alone and/or associated with invasive dental procedure. Bisphosphonates accumulate
almost exclusively in maxillofacial skeleton owing to high bone turn over remodeling to maintain the
mechanical competence. The pathogenesis and why it commonly appears in maxillofacial skeleton
and the fixed treatment strategies remains unknown. The aim of this study was to improve the
clinician understanding of N-BPs associated osteonecrosis of maxillofacial skeleton by reviewing
the past 10 year literature.
Source:
Dental Research Journal
Full
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| واژههای کلیدی: Nitrogen containing bisphosphonates، osteonecrosis of the jaw، staging and treatment strategies |
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نوع مطالعه: پژوهشي |
موضوع مقاله:
جراحی دهان، فک و صورت
دریافت: 1394/6/24 | پذیرش: 1394/6/24 | انتشار: 1394/6/24
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