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:: دوره 3، شماره 3 - ( مجموعه مقالات بیماری های دهان 1390 ) ::
جلد 3 شماره 3 صفحات 0-0 برگشت به فهرست نسخه ها
Dietary intervention for oral allergy syndrome as a treatment in orofacial granulomatosis: a new approach?
چکیده:   (1776 مشاهده)

 Background

 Orofacial granulomatosis (OFG) is a chronic granulomatous condition of the mouth, face and lips. Recent work demonstrates a high rate of atopy and silver birch sensitisation from skin prick testing (SPT). Oral allergy syndrome (OAS) is an acute oro-pharyngeal IgE mediated reaction, triggered by foods that cross react with pollens, most commonly silver birch. The aim of this study was to determine if patients with OFG and positive SPT to common OAS associated pollens responded to avoidance of cross reactive foods.

 Methods

 Patients with OFG and positive SPT to silver birch, grass, mugwort, ragweed and latex were required to avoid cross reacting foods, for 6 weeks and, in those who responded, for a total of 12 weeks. All had standardized oral examinations and were given severity scores (SS) at each appointment.

 Results

  Twenty two of 47 (47%) patients had one or more positive SPT and 13/22 completed 6 weeks on the diet. No difference was seen in SS between weeks 0 (14.62 ± 11.16) and 6 (13.31 ± 10.33 P = 0.656). Six of 14 (43%) had significantly improved SS (week 0 19.17 ± 12.95, week 6 10.83 ± 4.99, P = 0.027). Five completed 12 weeks and no further improvement was seen (week 6 11 ± 5.57, week 12 10.4 ± 9.94 P = 0.068). Two patients required no further treatments.

 Conclusions

  On an intention to treat basis, only 2/14 patients improved and required no further intervention. Whilst this diet cannot be recommended routinely, the improvement seen in some patients raises questions about the role of OAS in patients with OFG.


 Source: Journal of Oral Pathology & Medicine

 Full Text

واژه‌های کلیدی: oral allergy syndrome;orofacial granulomatosis
     
نوع مطالعه: پژوهشي | موضوع مقاله: بیماری های دهان
دریافت: 1392/8/4 | انتشار: 1390/10/25
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Dietary intervention for oral allergy syndrome as a treatment in orofacial granulomatosis: a new approach?. 1. 1390; 3 (3)

URL: http://idai.ir/article-1-2306-fa.html



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Creative Commons License این مقاله تحت شرایط Creative Commons Attribution-NonCommercial 4.0 International License قابل بازنشر است.
دوره 3، شماره 3 - ( مجموعه مقالات بیماری های دهان 1390 ) برگشت به فهرست نسخه ها
جامعه اسلامی دندانپزشکان Islamic Dental Association of IRAN

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