[Home ] [Archive]   [ فارسی ]  
Search in website

Advanced Search
..
:: Volume 4, Issue 4 (1-2012) ::
3 2012, 4(4): 0-0 Back to browse issues page
Aloe vera in the treatment for oral submucous fibrosis – a preliminary study
Abstract:   (2549 Views)

 Background and objectives:  Oral submucous fibrosis (OSMF) is a potentially malignant disorder of the oral mucosa, mainly associated with the practice of chewing gutka and betel quid. The pathogenesis is obscure, and till date, no definitive therapy is available for the management of OSMF. Hence, this preliminary study was carried out to compare the efficacy of Aloe vera with antioxidants in the treatment for OSMF.

  Methods:  Twenty study subjects with OSMF were included in the study. Patients were divided into two groups. There were 10 patients in each group group A subjects received 5 mg of aloe vera gel to be applied topically three times daily for 3 months and group B subjects received antioxidant capsules twice daily for 3 months. The results were analyzed with paired ‘t’ test and unpaired ‘t’ test.

  Results:  Aloe vera responded better in all the parameters assessed and responded in all the clinicohistopathological stages particularly in those with mild-stage clinically and early-stage histopathologically. Aloe vera showed a statistically significant reduction in burning sensation (P = 0.008), improvement in mouth opening (P = 0.02), and cheek flexibility (P = 0.01) on comparing with the antioxidant group.

 Interpretation and conclusion:  Overall assessment of the parameters depicted that Aloe vera group showed a better treatment response compared to the antioxidants group. It reduces the burning sensation and improves mouth opening thereby enhanced the patients’ compliance. It proves to be a relatively safe, can be applied topically, easily available, economical, noninvasive, and efficacious in the treatment for OSMF.


 Source: Journal of Oral Pathology & Medicine

 Full Text

Keywords: aloe vera;antioxidants;oral submucous fibrosis
     
Type of Study: Research | Subject: Oral and Maxillofacial Pathology
Received: 2012/12/19 | Published: 2012/01/15
Add your comments about this article
Your username or Email:

CAPTCHA


XML     Print


Download citation:
BibTeX | RIS | EndNote | Medlars | ProCite | Reference Manager | RefWorks
Send citation to:

Aloe vera in the treatment for oral submucous fibrosis – a preliminary study. 3 2012; 4 (4)
URL: http://idai.ir/article-1-862-en.html


Rights and permissions
Creative Commons License This work is licensed under a Creative Commons Attribution-NonCommercial 4.0 International License.
Volume 4, Issue 4 (1-2012) Back to browse issues page
جامعه اسلامی دندانپزشکان Islamic Dental Association of IRAN

کلیه حقوق سایت متعلق به جامعه اسلامی دندانپزشکان ایران است. تماس با ما

Persian site map - English site map - Created in 0.05 seconds with 36 queries by YEKTAWEB 4710