Materials and Methods: In the present descriptive study, with 212 participants, included were patients with no history of orthodontic treatment, loss or prosthetic replacement of anterior teeth, extracted teeth, lips with asymmetry or a history of trauma. Chi-square test was used to determine possible signifcances in the relation of smile line to Angle occlusion class, overbite and overjet and arch form. A P level of <0.05 was set as to be signifcant. 

Results: Chi-square test indicated that there was a signifcant difference between the smile design and overbite, overjet and gender but no statistically signifcant association was found between the smile design and crossbite, molar Angle classifcation and arch form. 

Conclusion: Within the limitations of such studies, it might be concluded that there is a signifcant and important relation between some occlusal parameters and smile design, which must be considered