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Laboratory methods and biomarkers in the evaluation of bisphosphonate effects on body tissues: a literature review
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چکیده: (2096 مشاهده) |
Bisphosphonates are extensively used to treat bone metabolism disorders meanwhile, these drugs have important side effects such as jaw osteonecrosis and femoral fracture. Therefore, studies have been conducted aimed at better understanding their mechanism of action and determining a course of action to avoid these side effects. We present here a literature review focusing on the laboratory methods available for investigating bisphosphonate effects on body tissues. There are many different methods available for this purpose, but the appropriate application of these methods and knowledge of their limitations are crucial for understanding the effects of bisphosphonates.
Source: Journal of Oral Pathology & Medicine Full Text |
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| واژههای کلیدی: biomarkers;bisphosphonates;body tissues;laboratory methods |
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نوع مطالعه: پژوهشي |
موضوع مقاله:
پاتولوزی دهان، فک و صورت
دریافت: 1392/8/6 | انتشار: 1390/10/25
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