fa Correlations between alveolar bone microstructure and bone turnover markers in pre- and post-menopausal women جراحی دهان، فک و صورت Oral and Maxillofacial Surgery پژوهشي Research <p> <strong>Objective</strong></p><p>  Alveolar cancellous bone biopsy samples were extracted during dental implant preparation for investigating microstructural changes due to menopause and relationships between these changes and bone turnover markers. </p><p> <strong>Study Design</strong></p><p>  Subjects were 18 women receiving mandibular implants: premenopausal (n = 5), early postmenopausal (≤5 years n = 3), and late postmenopausal (>5 years n = 10). Bone turnover markers were measured and the samples analyzed using microscopic computerized tomography and 3-dimensional bone morphometry. </p><p> <strong>Results</strong></p><p>  The alveolar bone volume was significantly less in late postmenopausal women than in premenopausal ones. The trabeculae in early postmenopausal women were more separated and rod-like than in premenopausal ones (P < .05). Each alveolar bone parameter was significantly (P < .05) related to at least 1 bone turnover marker. </p><p> <strong>Conclusions</strong></p><p>  Alveolar cancellous bone structure begins changing even in early postmenopausal women, and this structure varies in close relationship to bone turnover markers. </p><hr><p></p><p> <strong>Source: </strong>Oral Surgery, Oral Medicine, Oral Pathology, Oral Radiology </p><p> <a href="http://www.oooojournal.net/article/S2212-4403(12)00161-7/abstract" target="_blank"><font color="#0000ff">Full Text</font></a></p> 0 0 http://idai.ir/browse.php?a_code=A-10-32-1577&slc_lang=fa&sid=1 Emi Yamashita-Mikami 10031947532846007297 10031947532846007297 No Division of Comprehensive Prosthodontics, Department of Tissue Regeneration and Reconstruction, Niigata University Graduate School of Medical and Dental Sciences, Niigata, Japan Mikako Tanaka 10031947532846007298 10031947532846007298 Yes Division of Comprehensive Prosthodontics, Department of Tissue Regeneration and Reconstruction, Niigata University Graduate School of Medical and Dental Sciences, Niigata, Japan Naoki Sakurai 10031947532846007299 10031947532846007299 No Division of Comprehensive Prosthodontics, Department of Tissue Regeneration and Reconstruction, Niigata University Graduate School of Medical and Dental Sciences, Niigata, Japan Yoshiaki Arai 10031947532846007300 10031947532846007300 No Temporomandibular Joint Clinic, Niigata University Medical and Dental Hospital, Niigata, Japan Akira Matsuo 10031947532846007301 10031947532846007301 No Department of Oral and Maxillofacial Surgery, Tokyo Medical University, Tokyo, Japan Hayato Ohshima 10031947532846007302 10031947532846007302 No Division of Anatomy and Cell Biology of the Hard Tissue, Department of Tissue Regeneration and Reconstruction, Niigata University Graduate School of Medical and Dental Sciences, Niigata, Japan Shuichi Nomura 10031947532846007303 10031947532846007303 No Division of Comprehensive Prosthodontics, Department of Tissue Regeneration and Reconstruction, Niigata University Graduate School of Medical and Dental Sciences, Niigata, Japan Sadakazu Ejiri 10031947532846007304 10031947532846007304 No Department of Oral Anatomy, Division of Oral Structure, Function and Development, Asahi University School of Dentistry, Gifu, Japan