fa Survival of patients with pathologic T0N+ oral and oropharyngeal cancer after neoadjuvant therapy and surgery: the minority report جراحی دهان، فک و صورت Oral and Maxillofacial Surgery پژوهشي Research <p> <strong>Objectives </strong></p><p> Treatment outcome of patients with oral and oropharyngeal squamous cell carcinoma (OOSCC) achieving complete pathologic response at the primary site (ypT0) but incomplete response in loco-regional lymph nodes after preoperative chemoradiation (ypN+) is poorly described in the literature. This study's objective was to assess the survival of patients with OOSCC with ypT0N+ disease. </p><p> <strong>Study Design</strong></p><p>  176 patients with primary locally advanced OOSCC undergoing preoperative chemoradiotherapy were stratified according to the pathologic TNM classification into 6 groups: ypT0N0M0 (46%), ypT0N+M0 (10%), ypTNM I (24%), ypTNM II (4%), ypTNM III (6%), and ypTNM IV (10%).</p><p> <strong> Results</strong></p><p>  Three-year overall survival (OS) and recurrence-free survival (RFS) rates for the ypT0N+M0 group were both 61.8% and were similar to those of the ypTNM I group (OS 62.4% RFS rate of 59.2%). </p><p> <strong>Conclusions</strong></p><p>  Survival analyses showed that patients with OOSCC with ypT0N+ disease have a similar prognosis to those with pathologic TNM stage I. </p><hr><p></p><p> <strong>Source: </strong>Oral Surgery, Oral Medicine, Oral Pathology, Oral Radiology </p><p> <a href="http://www.oooojournal.net/article/S2212-4403(12)00364-1/abstract" target="_blank"><font color="#0000ff">Full Text</font></a></p> 0 0 http://idai.ir/browse.php?a_code=A-10-32-1541&slc_lang=fa&sid=1 Christos Perisanidis 10031947532846007090 10031947532846007090 Yes Department of Cranio-, Maxillofacial, and Oral Surgery, Medical University of Vienna, Vienna, Austria Iren Sulzbacher 10031947532846007091 10031947532846007091 No Department of Clinical Pathology, Medical University of Vienna, Vienna, Austria Martina Mittlböck 10031947532846007092 10031947532846007092 No Center for Medical Statistics, Informatics and Intelligent Systems, Section for Clinical Biometrics, Medical University of Vienna, Vienna, Austria David Mitchell 10031947532846007093 10031947532846007093 No Department of Oral and Maxillofacial Surgery, the Mid Yorkshire Hospitals NHS Trust, Wakefield, UK Cornelia Czembirek 10031947532846007094 10031947532846007094 No Department of Cranio-, Maxillofacial, and Oral Surgery, Medical University of Vienna, Vienna, Austria Radulf Seemann 10031947532846007095 10031947532846007095 No Department of Cranio-, Maxillofacial, and Oral Surgery, Medical University of Vienna, Vienna, Austria Rolf Ewers 10031947532846007096 10031947532846007096 No Department of Cranio-, Maxillofacial, and Oral Surgery, Medical University of Vienna, Vienna, Austria Christian Schopper 10031947532846007097 10031947532846007097 No Department of Cranio-, Maxillofacial, and Oral Surgery, Medical University of Vienna, Vienna, Austria Edgar Selzer 10031947532846007098 10031947532846007098 No Department of Radiotherapy, Medical University of Vienna, Vienna, Austria