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Do dental stem cells depict distinct characteristics? — Establishing their “phenotypic fingerprint”
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چکیده: (1323 مشاهده) |
Dental tissues provide an alternate source of stem cells compared with bone marrow and have a
similar potency as that of bone marrow derived mesenchymal stem cells. It has been established there
are six types of dental stem cells: Dental pulp stem cells, stem cells from human exfoliated deciduous
teeth, stem cells from apical papilla, periodontal ligament stem cells, dental follicle progenitor cells,
oral periosteum stem cells and recently gingival connective tissue stem cells . Most of the dental
tissues have a common developmental pathway thus, it is relevant to understand whether stem
cells derived from these closely related tissues are programmed differently. The present review
analyzes whether stem cells form dental tissues depict distinct characteristics by gaining insight
into differences in their immunophenotype. In addition, to explore the possibility of establishing
a unique phenotypic fingerprint of these stem cells by identifying the unique markers that can be
used to isolate these stem cells. This, in future will help in developing better techniques and markers
for identification and utilization of these stem cells for regenerative therapy.
Source:
Dental Research Journal
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| واژههای کلیدی: Dental papilla، dental pulp، dental sac، mesenchymal stem cells، periodontal ligament، stem cells |
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نوع مطالعه: پژوهشي |
موضوع مقاله:
پریودنتولوژی
دریافت: 1394/6/24 | پذیرش: 1394/6/24 | انتشار: 1394/6/24
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