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:: دوره 14، شماره 14 - ( عمومي 1390 ) ::
جلد 14 شماره 14 صفحات 0-0 برگشت به فهرست نسخه ها
The development of a new desensitising mouthwash containing arginine, PVM/MA copolymer, pyrophosphates, and sodium fluoride—A hydraulic conductance study
چکیده:   (2483 مشاهده)

 Objective

  To investigate the ability of a novel mouthwash comprised of 0.8% arginine, PVM/MA copolymer, pyrophosphates, and 0.05% sodium fluoride in an alcohol-free base (Pro-Argin™ Mouthwash Technology) to reduce dentine permeability.

 Methods

  Hydraulic conductance was used to assess the dentine permeability effects of the arginine mouthwash. Aqueous solutions containing arginine and PVM/MA copolymer were studied in the initial stage of the method development. The acid resistance was tested with a cola drink challenge. Finally, a blinded study was carried out to determine the occlusion of the arginine mouthwash in comparison to a negative control mouthwash.

 Results

  Dentine discs treated with the arginine mouthwash showed an average fluid reduction of 42%, which was statistically, significantly better than the fluid reduction for the negative control mouthwash. In addition, experiments using simple solutions of arginine and PVM/MA copolymer, alone and in combination, demonstrated that the combination of the two was required to provide a relevant occlusion benefit. Finally, the occlusion provided by the arginine mouthwash was maintained after exposure to an acid challenge.

  Conclusion

  The exclusive combination of ingredients in the arginine mouthwash has been proven to be efficacious in decreasing dentine fluid flow as measured by hydraulic conductance. The new mouthwash works by occlusion, due to the unique combination of arginine, PVM/MA copolymer and pyrophosphates.


 Source: Journal of Dentistry

 Full Text

واژه‌های کلیدی: Mouthwash، Tooth sensitivity، Arginine، PVM/MA copolymer، Tubule occlusion، Dentine
     
نوع مطالعه: پژوهشي | موضوع مقاله: مقالات عمومي
دریافت: 1392/7/13 | پذیرش: 1393/4/2 | انتشار: 1393/4/2
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The development of a new desensitising mouthwash containing arginine, PVM/MA copolymer, pyrophosphates, and sodium fluoride—A hydraulic conductance study. 1. 1390; 14 (14)

URL: http://idai.ir/article-1-2151-fa.html



بازنشر اطلاعات
Creative Commons License این مقاله تحت شرایط Creative Commons Attribution-NonCommercial 4.0 International License قابل بازنشر است.
دوره 14، شماره 14 - ( عمومي 1390 ) برگشت به فهرست نسخه ها
جامعه اسلامی دندانپزشکان Islamic Dental Association of IRAN

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