en اندودانتیکس Endodontics پژوهشي Research <p> <strong>Introduction:</strong> Ca(OH)2-containing/forming materials are conventionally used for indirect pulp-capping and are theoretically able to release Ca2+ and OH- ions for hydrolytic dissociation. However, no evidence exists for ion diffusion through the remaining coronal dentin. The aim of this study was to design an innovative experimental set-up to test the ability of Ca(OH)2-containing and Ca(OH)2-forming pulp-capping materials to generate pulpward Ca2+ and OH- ion fluxes through coronal dentin after indirect pulp-capping in vitro. </p><p> <strong>Materials and Methods:</strong> Standardized class 1 cavities were prepared in erupted sound human molars. Pulp tissue was excised. A coronal Remaining Dentin Thickness (RTD) (1±0.2 mm thick) was prepared within an occlusal-to-pulp cavity system (coronal RD system). The whole system/sample was treated with 17% EDTA to remove the smear layer and the external surface was covered by nail varnish. Indirect pulp-capping was performed on coronal RDT using a conventional pulp-capping material covered by a glass ionomer cement, a composite and nail varnish. Chemically different Ca(OH)2 materials were used to test the reliability of the set-up. The leached Ca2+ and OH- ions were measured using ion-selective electrodes after soaking for 3 hours, 24 hours, and 7 days in deionized water (10 mL, 37°C). </p><p> <strong>Results:</strong> Calcium ions were detected and a rise in pH was observed in the treated water after a few hours for all tested materials. <strong></strong></p><p> <strong>Conclusion:</strong> The experimental set-up proved to be an easy and effective method for testing the different Ca(OH)2-containing and Ca(OH)2-forming materials ability to induce a pulpward flux of calcium and hydroxyl ions through coronal remaining dentin after indirect pulp-capping. The new system will allow the screening of current pulp-capping materials. </p><hr><p></p><p> <strong>Source: </strong>Iranian Endodontic Journal </p><p><a href="http://journals.sbmu.ac.ir/index.php/iej/article/view/3159" target="_blank"><font color="#0033ff"> Full Text</font></a> </p> Calcium; Calcium Hydroxide; Dentin; Diffusion; Dycal; Dental Materials; Endodontics; Pulp Cap; ProRoot; Mineral Trioxide Aggregate; Pulpdent Paste; Dental Pulp Exposure 0 0 http://idai.ir/browse.php?a_code=A-10-32-812&slc_lang=en&sid=1 Maria Giovanna Gandolfi mgiovanna.gandolfi@unibo.it 10031947532846003570 10031947532846003570 Yes Laboratory of Biomaterials and Oral Pathology, Department of Odontostomatological Sciences, University of Bologna, Bologna, Italy