2

en Effect of Estrogen and Dietary Loading on Condylar Cartilage ارتودنسی Orthodontics پژوهشي Research Aims: To study the effect of estrogen deficiency and altered temporomandibular joint loading on the histomorphology of condylar cartilage and on the expression of types II and X collagen and matrix metalloproteinase-3 (MMP-3). Methods: Thirty-six female rats were divided into four groups: ovariectomized rats on a normal diet, nonovariectomized control rats on a normal diet, ovariectomized rats on a soft diet, and nonovariectomized control rats on a soft diet. Ovariectomy was performed at the age of 60 days. Repeated measures ANOVA was used to analyze the data. Results: The condylar cartilage in the ovariectomized normal diet group showed a significantly higher number of cells than in the nonovariectomized control rats (P < .001). The proportional amount of MMP-3 expression was significantly higher in the ovariectomized rats than in the nonovariectomized control rats in both diet groups (P < .001). The area covered by types II and X collagen was significantly higher in the experimental groups than in the control groups (P < .01). Conclusion: Condylar cartilage is sensitive to both estrogen level and dietary loading. <hr> Source: Journal Of Orofacial Pain <a href="http://jop.quintessenz.de/index.php?jid=jop&doc=toc&year=2012&issue=4">Full Text</a> estrogen, joint loading, mandibular condylar cartilage, MMP-3, type II collagen, type X collagen 0 0 http://idai.ir/browse.php?a_code=A-10-32-807&slc_lang=en&sid=1 Marko Orajärvi 10031947532846003543 10031947532846003543 Yes Shi-Bin Yu 10031947532846003544 10031947532846003544 No Xiaodong Liu 10031947532846003545 10031947532846003545 No Petri Tiilikainen 10031947532846003546 10031947532846003546 No Meiqing Wang 10031947532846003547 10031947532846003547 No Aune Raustia 10031947532846003548 10031947532846003548 No Pertti Pirttiniemi 10031947532846003549 10031947532846003549 No