en پاتولوزی دهان، فک و صورت Oral and Maxillofacial Pathology پژوهشي Research <p> Background and aims. Well-differentiated chondrosarcoma and enchondroma are similar in histopathologic aspects therefore, special methods should be used to make a distinction between these benign and malignant tumors. The aim of this study was to evaluate the efficacy of a histopathologic method in the long-term follow-up for differentiating these lesions.<br>Materials and methods. The medical records of patients with histopathologic diagnosis of chondrosarcoma and en-chondroma were retrieved from the Institute of Cancer, Department of Pathology from 1981 to 2007 in this retrospective study. A total of 14 patients with chondrosarcoma and 7 patients with enchondroma were included. Tumor lobulation pat-tern and fibrous tissue around the lesions were used for histopathologic differentiation between well-differentiated chon-drosarcoma and enchondroma. Method accuracy was evaluated by tumor recurrence in the long-term follow-up.<br>Results. In the well-differentiated chondrosarcoma group, the follow-up period was 97 months. All the patients (100%) experienced recurrence. In the enchondroma group, the follow-up period was 129 months. There was no recurrence in this group.<br>Conclusion. Lobulation pattern and fibrous tissue formation around the tumor can be an effective and helpful indicator for histopathologic differentiation between enchondroma and well-differentiated chondrosarcoma. </p><hr><p></p><p> <strong>Source:</strong> Journal of Dental Research, Dental Clinics, Dental Prospects</p><p><a href="http://dentistry.tbzmed.ac.ir/joddd/index.php/joddd/article/view/297" target="_blank"><font color="#0000cc"> Full text</font></a></p> Enchondroma, Chondrosarcoma, Histopathologic differentiation, Clinical follow-up 0 0 http://idai.ir/browse.php?a_code=A-10-32-520&slc_lang=en&sid=1 Shams Shariat Torbaghan 10031947532846002124 10031947532846002124 No Faculty of Dentistry, Shahed University, Tehran, Iran Mahdi Ashouri 10031947532846002125 10031947532846002125 No Noushin Jalayer Naderi noushin_jly85@yahoo.com 10031947532846002126 10031947532846002126 Yes Faculty of Dentistry, Shahed University, Tehran, Iran Nima Baherini 10031947532846002127 10031947532846002127 No