fa Discordant tooth agenesis and peg-shaped in a pair of monozygotic twins: Clinical and molecular study کودکان Pediatric Dentistry پژوهشي Research The present report aimed to study an uncommon case of a pair of twins that presented a discordant dental phenotype. Family investigation, clinical, radiographic examination and molecular analysis were performed in both girls. Molecular analysis confirmed the monozygosity by deoxyribonucleic acid chip technology. One twin presented tooth agenesis in left upper lateral incisor and peg-shaped on the contra lateral side while the other twin had no dental alterations. The dental casts study employed digital caliper to compare morphological dimensions and showed alteration only in peg-shaped tooth. In conclusion, this study provide support that one or more mutated gene could cause discordances in dental phenotype in these monozygotic twins.<hr><p class="MsoNormal" style="text-align: left direction: ltr unicode-bidi: embed"><b>Source: </b>Dental Research Journal </p> <p class="MsoNormal" style="text-align: left direction: ltr unicode-bidi: embed"><a href="http://drj.mui.ac.ir/index.php/drj/article/view/1533" target="_blank"><font color="#0000ff">Full Text</font></a></p> Dental anomalies, dental development, monozygotic twins, tooth agenesis 0 0 http://idai.ir/browse.php?a_code=A-10-32-3416&slc_lang=fa&sid=1 Lívia Azeredo Alves Antunes liviaazeredo@ gmail.com 100319475328460015677 100319475328460015677 Yes Department of Specific Formation, School of Dentistry, Fluminense Federal University, Nova Friburgo Erika Calvano Küchler 100319475328460015678 100319475328460015678 No Unit of Clinical Research, Fluminense Federal University, Niterói Marcelo de Castro Costa 100319475328460015679 100319475328460015679 No Department of Pediatric Dentistry and Orthodontics, School of Dentistry, Federal University of Rio de Janeiro, Rio de Janeiro Leonardo Santos Antunes 100319475328460015680 100319475328460015680 No Department of Specific Formation, School of Dentistry, Fluminense Federal University, Nova Friburgo José Mauro Granjeiro 100319475328460015681 100319475328460015681 No National Institute of Metrology, Quality and Technology, Head of Bioengineering Program, and Head of Cell Therapy Center, Unit of Clinical Research, Fluminense Federal University, all in Rio de Janeiro, Brazil