en پاتولوزی دهان، فک و صورت Oral and Maxillofacial Pathology پژوهشي Research <div class="para"><p><b>Background: </b> Oral verrucous hyperplasia (VH) and verrucous carcinoma (VC) are two clinicopathologically distinctive oral verrucous lesions. The objective of this study was to investigate the clinicopathological features of the two verrucous lesions and estimate their relationship from China.</p></div><div class="para"><p><b>Methods: </b> Retrospective review of two series of patients with histologically confirmed VH (<em>n</em> = 121) and VC (<em>n</em> = 56) between 1996 and 2009 in our hospital were conducted.</p></div><div class="para"><p><b>Results: </b> The average age of VH was 58.5 years (ratio male:female = 1.37) with the tongue being the predominant site. The average age of VC was 64.3 years (ratio male:female = 1.15) with the lower lip being the predominant site. Multivariate analysis revealed that the elderly patient with verrucous lesion (≥60 years) was associated with 3.06-fold (<em>P</em> = 0.007) increased carcinoma risk compared with the non-elderly patient. The lesion located on lower lip was associated with 13.54-fold (<em>P</em> < 0.001) increased carcinoma risk compared with other sites.</p></div><div class="para"><p><b>Conclusion: </b> Clinicopathological features of VH and VC in China were elucidated. Elderly patient with oral verrucous lesion located on the lower lip correlates with higher risk of carcinoma.</p><p><hr></p><font size="3"><p dir="ltr"><strong>Source:</strong> Journal of Oral Pathology & Medicine</p><p dir="ltr"><a href="http://onlinelibrary.wiley.com/doi/10.1111/j.1600-0714.2011.01078.x/abstract" target="_blank"><font color="#0000cc">Full text</font></a></p></font></div> clinicopathological feature,oral verrucous carcinoma,oral verrucous hyperplasia 0 0 http://idai.ir/browse.php?a_code=A-10-32-304&slc_lang=en&sid=1 Lai-Kuan Zhu 10031947532846001267 10031947532846001267 Yes Ye-Wei Ding 10031947532846001268 10031947532846001268 No Wei Liu 10031947532846001269 10031947532846001269 No Yong-Mei Zhou 10031947532846001270 10031947532846001270 No Lin-Jun Shi 10031947532846001271 10031947532846001271 No Zeng-Tong Zhou 10031947532846001272 10031947532846001272 No