fa Formulation and Characterization of Antibacterial Fluoride-releasing Sealants کودکان Pediatric Dentistry پژوهشي Research <p> <strong>Purpose:</strong></p><p>  The purpose of this study was to formulate and characterize experimental antibacterial fluoride-releasing sealants and compare them with commercial sealants for fluoride release, recharge, adhesion, and microleakage. </p><p> <strong>Methods:</strong> </p><p> Two experimental sealants (Exp-1, Exp-2) containing a synthesized antibacterial fluoride-releasing monomer and fluoride-releasing filler were formulated. Exp-2 also contained NovaMin nanoparticles. Commercial sealants Clinpro (CL) FluroShield (FS), and SeLECT Defense (E34) were also included. Fluoride release from disk samples in deionized water was measured daily using an ion-selective electrode for 14 days, and after recharging with Neutra-Foam (2.0% sodium fluoride), fluoride was measured for 5 days. Microtensile bonding strengths (MTBS) to enamel were tested after 24-hour storage in water at 37°C or thermocycling 5-55°C for 1,000 cycles. A microleakage test was conducted on extracted teeth using a dye-penetration method. The data were analyzed using analysis of variance with the Tukey's honestly significant difference test and Kruskal-Wallis test. </p><p> <strong>Results:</strong></p><p>  Exp-1 and Exp-2 had significantly higher fluoride release and recharge capabilities than CL and FL (P<.05). All tested sealants had similar MTBS before and after thermocycling. Exp-2 and Exp-1 had significantly lower microleakage scores (P<.05) than other groups. </p><p> <strong>Conclusion</strong><strong>:</strong></p><p> <strong> </strong>The experimental sealants had higher fluoride release and recharge capabilities and similar or better retention than commercial sealants. </p><hr><p></p><p> <strong>Source: </strong>Journal of American Academy of ‍ Pediatric Dentistry</p><p><a href="http://www.ingentaconnect.com/content/aapd/pd/2013/00000035/00000001/art00017" target="_blank"><font color="#0000ff"> Full Text</font></a></p> ANTIBACTERIAL; FLUORIDE RELEASE; MICROLEAKAGE; MICROTENSILE BOND STRENGTH; SEALANTS 0 0 http://idai.ir/browse.php?a_code=A-10-32-2508&slc_lang=fa&sid=1 Yuwei Fan 100319475328460011929 100319475328460011929 Yes Department of Comprehensive Dentistry and Biomaterials, Louisiana State University Health Sciences Center, New Orleans, La., USA Janice Townsend 100319475328460011930 100319475328460011930 No Department of Pediatric Dentistry, Louisiana State University Health Sciences Center, New Orleans, La., USA Yapin Wang 100319475328460011931 100319475328460011931 No Department of Comprehensive Dentistry and Biomaterials, Louisiana State University Health Sciences Center, New Orleans, La., USA Eun Chee Lee 100319475328460011932 100319475328460011932 No School of Dentistry, Louisiana State University Health Sciences Center, New Orleans, La., USA Katie Evans 100319475328460011933 100319475328460011933 No School of Dentistry, Louisiana State University Health Sciences Center, New Orleans, La., USA Erica Hender 100319475328460011934 100319475328460011934 No School of Dentistry, Louisiana State University Health Sciences Center, New Orleans, La., USA Joseph L. Hagan 100319475328460011935 100319475328460011935 No School of Public Health, Louisiana State University Health Sciences Center, New Orleans, La., USA Xiaoming Xu 100319475328460011936 100319475328460011936 No Division of Biomaterials, Department of Comprehensive Dentistry and Biomaterials, Louisiana State University Health Sciences Center, New Orleans, La., USA