fa In situ effect of chewing gum containing CPP–ACP on the mineral precipitation of eroded bovine enamel—A surface hardness analysis ترمیمی Cosmetic and Restorative Dentistry پژوهشي Research <p> <strong>Objectives</strong></p><p>  Stimulation of salivary flow is considered a preventive strategy for dental erosion. Alternatively, products containing calcium phosphate, such as a complex of casein phosphopeptide–amorphous calcium phosphate (CPP–ACP), have also been tested against dental erosion. Therefore, this in situ study analyzed the effect of chewing gum containing CPP–ACP on the mineral precipitation of initial bovine enamel erosion lesions. <strong></strong></p><p> <strong>Methods</strong> </p><p> Twelve healthy adult subjects wore palatal appliances with two eroded bovine enamel samples. The erosion lesions were produced by immersion in 0.1% citric acid (pH 2.5) for 7min. During three experimental crossover in situ phases (1 day each), the subjects chewed a type of gum, 3 times for 30min, in each phase: with CPP–ACP (trident total), without CPP–ACP (trident), and no chewing gum (control). The Knoop surface microhardness was measured at baseline, after erosion in vitro and the mineral precipitation in situ. The differences in the degree of mineral precipitation were analyzed using repeated measures (RM-) ANOVA and post hoc Tukey's test (p<0.05).</p><p> <strong> Results</strong></p><p>  Significant differences were found among the remineralizing treatments (p<0.0001). Chewing gum (19% of microhardness recovery) improved the mineral precipitation compared to control (10%) and the addition of CPP–ACP into the gum promoted the best mineral precipitation effect (30%). </p><p> <strong>Conclusions</strong></p><p> <strong> </strong>Under this protocol, CPP–ACP chewing gum improved the mineral precipitation of eroded enamel. </p><p> <strong>Clinical significance</strong></p><p>  Since the prevalence of dental erosion is steadily increasing, CPP–ACP chewing gum might be an important strategy to reduce the progression of initial erosion lesions. </p><hr><p></p><p> <strong>Source: </strong>Journal of Dentistry</p><p><a href="http://www.jodjournal.com/article/S0300-5712(13)00155-3/abstract" target="_blank"><font color="#0000ff"> Full Text</font></a></p> Casein phosphopeptide–amorphous calcium phosphate, Enamel, Erosion, Hardness 0 0 http://idai.ir/browse.php?a_code=A-10-32-2187&slc_lang=fa&sid=1 Letícia Prestes 100319475328460010284 100319475328460010284 No Department of Biological Sciences, Bauru School of Dentistry/University of São Paulo, Al. Octávio Pinheiro Brisolla, 9-75, 17012-901 Bauru, SP, Brazil Beatriz M. Souza 100319475328460010285 100319475328460010285 No Department of Biological Sciences, Bauru School of Dentistry/University of São Paulo, Al. Octávio Pinheiro Brisolla, 9-75, 17012-901 Bauru, SP, Brazil Lívia P. Comar 100319475328460010286 100319475328460010286 No Department of Biological Sciences, Bauru School of Dentistry/University of São Paulo, Al. Octávio Pinheiro Brisolla, 9-75, 17012-901 Bauru, SP, Brazil Priscila A. Salomão 100319475328460010287 100319475328460010287 No Department of Biological Sciences, Bauru School of Dentistry/University of São Paulo, Al. Octávio Pinheiro Brisolla, 9-75, 17012-901 Bauru, SP, Brazil Daniela Rios 100319475328460010288 100319475328460010288 No Department of Pediatric Dentistry, Orthodontics and Public Health, Bauru School of Dentistry/University of São Paulo, Al. Octávio Pinheiro Brisolla, 9-75, 17012-901 Bauru, SP, Brazil Ana Carolina Magalhães 100319475328460010289 100319475328460010289 Yes Department of Biological Sciences, Bauru School of Dentistry/University of São Paulo, Al. Octávio Pinheiro Brisolla, 9-75, 17012-901 Bauru, SP, Brazil