fa Ion release and physical properties of CPP–ACP modified GIC in acid solutions سلامت دهان و جامعه نگر Oral Health and Epidemiology پژوهشي Research <p> <strong>Objectives</strong></p><p>  To assess this new GIC compared with a GIC without CPP–ACP (Fuji VII™) with respect to ion release, changes in surface hardness and in mass under a variety of acidic and neutral conditions. </p><p> <strong>Methods</strong></p><p>  Eighty blocks of Fuji VII™ (F7) and Fuji VII™ EP (F7EP) were subjected to three acidic solutions (lactic and citric acids pH 5.0, hydrochloric acid pH 2.0) and water (pH 6.9) over a three-day period. Ion release, surface hardness and weight measurements were carried out every 24h. </p><p> <strong>Results</strong></p><p>  Higher calcium ion release from F7EP was observed under all acidic conditions. Increased inorganic phosphate ion release was observed for F7EP in hydrochloric and citric acids. Fluoride ion release was similar between F7 and F7EP under all conditions but was significantly higher in acids compared with water. After three days there was no significant difference in surface hardness (p>0.05) between the two materials under all conditions except hydrochloric acid. Minimal change in mass was observed for F7 and F7EP in water, lactic and hydrochloric acids, however citric acid caused significantly more mass loss compared with water (p<0.001).</p><p> <strong> Conclusion</strong> </p><p> Incorporation of 3% (w/w) CPP–ACP into F7 enhanced calcium and phosphate ion release, with no significant change in fluoride ion release and no adverse effects on surface hardness or change in mass.</p><p> <strong> Clinical significance</strong></p><p>  statement GICs have the potential to release fluoride ions particularly under acidic conditions associated with dental caries and erosion. A new GIC containing CPP–ACP and fluoride releases not only fluoride ions but also calcium and phosphate ions under acidic conditions which should help to inhibit demineralisation associated with caries and erosion. </p><hr><p></p><p> <strong>Source: </strong>Journal of Dentistry</p><p> <a href="http://www.jodjournal.com/article/S0300-5712(13)00048-1/abstract" target="_blank"><font color="#0000ff">Full Text</font></a></p> GIC, CPP–ACP, Hardness, Ion release 0 0 http://idai.ir/browse.php?a_code=A-10-32-2152&slc_lang=fa&sid=1 I. Zalizniak 100319475328460010105 100319475328460010105 No Oral Health CRC, Melbourne Dental School, The University of Melbourne, Australia J.E.A. Palamara 100319475328460010106 100319475328460010106 No Oral Health CRC, Melbourne Dental School, The University of Melbourne, Australia R.H.K. Wong 100319475328460010107 100319475328460010107 No Oral Health CRC, Melbourne Dental School, The University of Melbourne, Australia N.J. Cochrane 100319475328460010108 100319475328460010108 No Oral Health CRC, Melbourne Dental School, The University of Melbourne, Australia M.F. Burrow 100319475328460010109 100319475328460010109 No Faculty of Dentistry, University of Hong Kong, Hong Kong E.C> Reynolds 100319475328460010110 100319475328460010110 Yes Oral Health CRC, Melbourne Dental School, The University of Melbourne, Australia