fa Efficacy of a mouthwash containing 0.8% arginine, PVM/MA copolymer, pyrophosphates, and 0.05% sodium fluoride compared to a commercial mouthwash containing 2.4% potassium nitrate and 0.022% sodium fluoride and a control mouthwash containing 0.05% sodium fluoride on dentine hypersensitivity: A six-week randomized clinical study مقالات عمومي General پژوهشي Research <p> <strong>Objective</strong></p><p>  Evaluate the efficacy of 0.8% arginine, potassium nitrate and sodium fluoride mouthwashes on dentine hypersensitivity reduction.</p><p> <strong> Methods</strong></p><p>  Six week randomized, double blinded, two cell, parallel single centre clinical study in the Dominican Republic subjects were randomized into three treatment groups: mouthwash containing 0.8% arginine, PVM/MA copolymer, pyrophosphates, and 0.05% sodium fluoride in an alcohol-free base (arginine) mouthwash containing 2.4% potassium nitrate and 0.022% sodium fluoride (potassium nitrate) a control mouthwash containing 0.05% sodium fluoride (negative control). Tactile and air-blast dentine hypersensitivity assessments were conducted at baseline, thirty minutes post rinsing and two, four, and six weeks of twice-daily product use. For treatment group comparisons, ANCOVA and post hoc Tukey's pair-wise comparisons (α=0.05) were done. </p><p> <strong>Results</strong></p><p>  Seventy-five subjects were enrolled 69 subjects completed the study. There were no differences after thirty minutes of a single use, among the three groups with respect to mean tactile and air blast hypersensitivity scores compared to potassium nitrate and negative control mouthwashes (p<0.05). The arginine group presented a statistically significant improvement in the mean tactile scores compared to potassium nitrate and negative control groups after two, four, and six weeks (p<0.001) of product use the arginine group showed a statistically significant enhancement in air blast hypersensitivity mean scores compared to potassium nitrate and negative control groups after two (p=0.001), four (p<0.001), and six weeks (p<0.001) of product use. </p><p> <strong>Conclusion</strong></p><p>  A mouthwash containing arginine provides a significant and superior reduction in dentine hypersensitivity compared to potassium nitrate and a negative control mouthwash after two weeks. </p><hr><p></p><p> <strong>Source: </strong>Journal of Dentistry</p><p> <a href="http://www.jodjournal.com/article/S0300-5712(12)00306-5/abstract" target="_blank"><font color="#0000ff">Full Text</font></a></p> Efficacy, Dentinal, Hypersensitivity, Mouthwash, Tactile, Air blast 0 0 http://idai.ir/browse.php?a_code=A-10-32-2129&slc_lang=fa&sid=1 Augusto R. Elías Boneta 10031947532846009983 10031947532846009983 Yes University of Puerto Rico, School of Dental Medicine, San Juan, Puerto Rico Rafael M. Galán Salás 10031947532846009984 10031947532846009984 No Rosa Duarte # 20, Gazcue, Santo Domingo, Dominican Republic Luis R. Mateo 10031947532846009985 10031947532846009985 No LRM Statistical Consulting, Hoboken, NJ, USA Bernal Stewart 10031947532846009986 10031947532846009986 No Colgate-Palmolive Technology Center, Piscataway, NJ, USA Sarita Mello 10031947532846009987 10031947532846009987 No Colgate-Palmolive Technology Center, Piscataway, NJ, USA Lia S. Arvanitidou 10031947532846009988 10031947532846009988 No Colgate-Palmolive Technology Center, Piscataway, NJ, USA Foti Panagakos 10031947532846009989 10031947532846009989 No Colgate-Palmolive Technology Center, Piscataway, NJ, USA William De Vizio 10031947532846009990 10031947532846009990 No Colgate-Palmolive Technology Center, Piscataway, NJ, USA