fa Inhibition of enamel mineral loss by fissure sealant: An in situ study کودکان Pediatric Dentistry پژوهشي Research <p> <strong>Objectives</strong></p><p>  This study evaluated the effect of fluoride and non-fluoride sealants on hardness decrease (HD) and marginal adaptation (MA) on enamel substrates after cariogenic challenge.</p><p> <strong> Methods</strong></p><p>  Occlusal enamel blocks, from human third molars, were randomly divided into six groups (n=12), according to occlusal fissures condition (S – sound C – caries-like lesion CF – caries-like lesion+topical fluoride) and sealants (F – FluroShield H – Helioseal Clear Chroma). Lesion depths were 79.3±33.9 and 61.3±23.9 for C and CF groups, respectively. Sealants were placed on occlusal surface and stored at 100% humidity (37°C 24h/d). HD was measured by cross-sectional microhardness analysis at the sealant margin distances: −1 (under sealant), 0 (sealant margin), 1, 2 (outer sealant). Sealant MA was observed by polarized light microscopy and scored according to: 0 – failure (no sealant MA or total sealant loss) 1 – success (sealant MA present). MA and HD were analysed by ANOVA-R and mixed model analysis, respectively.</p><p> <strong> Results</strong></p><p>  For HD (ΔS), F values (6900.5±3686.6) were significantly lower than H values (8534.6±5375.3) regardless of enamel substrates and sealant margin distances. Significant differences were observed among sealant margin distances: −1 (5934.0±3282.6)<0 (8701.5±6175.7)=1 (8473.2±4299.4)=2 (7761.5±4035.1), regardless of sealant and substrate. MA was similar for all groups (p≥0.05). </p><p> <strong>Conclusion</strong></p><p>  MA was not affected by sealant type or substrate condition, whereas enamel HD was favourably impacted by fluoride in the sealant. In addition, sealants were more effective as a physical barrier than as its chemical potency in reducing enamel HD. </p><p> <strong>Clinical significance</strong> </p><p> Sealing with a fluoride material is a recommended procedure to prevent caries of occlusal permanent molars in high-caries-risk patients, even though those exhibiting white spot lesions, since the enamel hardness decrease when fluoride sealant was used in vitro. </p><hr><p></p><p> <strong>Source: </strong>Journal of Dentistry</p><p> <a href="http://www.jodjournal.com/article/S0300-5712(12)00274-6/abstract" target="_blank"><font color="#0000ff">Full Text</font></a></p> Dental enamel, Dental caries, In situ model, Occlusal surface, Sealants, Tooth remineralization, White spots 0 0 http://idai.ir/browse.php?a_code=A-10-32-2095&slc_lang=fa&sid=1 Kamila Rosamilia Kantovitz 10031947532846009810 10031947532846009810 Yes Fernanda Miori Pascon 10031947532846009811 10031947532846009811 No Francisco Humberto Nociti 10031947532846009812 10031947532846009812 No Cinthia P. Machado Tabchoury 10031947532846009813 10031947532846009813 No Regina Maria Puppin-Rontan 10031947532846009814 10031947532846009814 No