fa Ten-year retrospective study of head and neck carcinoma in situ: incidence, treatment, and clinical outcome جراحی دهان، فک و صورت Oral and Maxillofacial Surgery پژوهشي Research <p> <strong>Objectives</strong></p><p>  To examine the management and clinical outcome for patients with primary head and neck carcinoma in situ (CIS) and to estimate the incidence in the referral population.</p><p> <strong> Study design</strong></p><p>  A retrospective study from 2000-2009 of patients with head and neck CIS referred for treatment at Rigshospitalet. The referral area was East Denmark and Greenland with a population of 2.4 million. </p><p> <strong>Results</strong> </p><p> Fifty-five patients with primary CIS were identified: 21 oral cavity, 7 pharynx, 25 larynx, 2 nasal cavity/paranasal sinuses. The median annual incidence was 0.24/100,000. Eleven patients (20%) had T-site recurrence. The 5-year disease-specific survival rate and 5-year recurrence-free survival rate were 98% and 74% respectively. </p><p> <strong>Conclusions</strong></p><p>  The annual incidence of primary head and neck CIS was low and in accordance with previous findings reported in the literature. We recommend that CIS lesions should be treated on T-site and surveilled as T1/T2 head and neck carcinomas. </p><hr><p></p><p> <strong>Source: </strong>Oral Surgery, Oral Medicine, Oral Pathology, Oral Radiology </p><p> <a href="http://www.oooojournal.net/article/S2212-4403(13)00118-1/abstract" target="_blank"><font color="#0000ff">Full Text</font></a></p> 0 0 http://idai.ir/browse.php?a_code=A-10-32-1671&slc_lang=fa&sid=1 A. Christensen 10031947532846007841 10031947532846007841 Yes Department of Otolaryngology-Head and Neck Surgery and Audiology, Rigshospitalet, Copenhagen University Hospital, Copenhagen, Denmark E. Khristensen 10031947532846007842 10031947532846007842 No Department of Pathology, Rigshospitalet, Copenhagen University Hospital, Copenhagen, Denmark M.H. Terkildsen 10031947532846007843 10031947532846007843 No Department of Pathology, Rigshospitalet, Copenhagen University Hospital, Copenhagen, Denmark L. Specht 10031947532846007844 10031947532846007844 No Department of Oncology, Rigshospitalet, Copenhagen University Hospital, Copenhagen, Denmark J. Reibel 10031947532846007845 10031947532846007845 No Department of Oral Medicine, Clinical Oral Physiology, Oral Pathology and Anatomy, School of Dentistry, Faculty of Health Sciences, University of Copenhagen, Copenhagen, Denmark P. Homøe 10031947532846007846 10031947532846007846 No Department of Otolaryngology-Head and Neck Surgery and Audiology, Rigshospitalet, Copenhagen University Hospital, Copenhagen, Denmark