fa The effect of anodized implants coated with combined rhBMP-2 and recombinant human vascular endothelial growth factors on vertical bone regeneration in the marginal portion of the peri-implant جراحی دهان، فک و صورت Oral and Maxillofacial Surgery پژوهشي Research <p> <strong>Objectives </strong></p><p> The aim of this study was to evaluate the effect of anodized implants coated with combined rhBMP-2 and recombinant human vascular endothelial growth factors (rhVEGFs) on vertical bone regeneration in the marginal portion of the peri-implant. </p><p> <strong>Study Design</strong></p><p>  Supra-alveolar defects were created in 3 male beagle dogs. Each animal received 8 implants that were either coated with a single growth factor (rhBMP-2) or combined growth factors (rhBMP-2 + rhVEGF), or an anodized implant (the control group). The amount of the vertical bone regeneration, the bone-implant contact, and the intrathread bone density were investigated using histomorphometric analysis at 8 weeks. </p><p> <strong>Results</strong></p><p>  The bone morphogenetic protein (BMP) group and the BMP-VEGF group showed vertical alveolar bone regeneration and enhanced bone-implant contact in the microthread compared with the control group (P < .05). </p><p> <strong>Conclusions</strong></p><p>  Anodized implants coated with rhBMP-2 and rhBMP - 2 + rhVEGF can induce vertical alveolar bone regeneration, but the combined effect of rhBMP-2 and rhVEGF was not verified. </p><hr><p></p><p> <strong>Source: </strong>Oral Surgery, Oral Medicine, Oral Pathology, Oral Radiology </p><p><a href="http://www.oooojournal.net/article/S2212-4403(12)00174-5/abstract" target="_blank"><font color="#0000ff"> Full Text</font></a></p> 0 0 http://idai.ir/browse.php?a_code=A-10-32-1629&slc_lang=fa&sid=1 Jong-Eun Kim 10031947532846007577 10031947532846007577 No Advanced Prosthodontics, Postgraduate School of Clinical Dentistry, Institute for Clinical Dental Research, Korea University, Seoul, Korea Seong-Su Kang 10031947532846007578 10031947532846007578 No College of Veterinary Medicine, Chonnam National University, Gwangju, Korea Kyung-Hee Choi 10031947532846007579 10031947532846007579 No Research and Development Institute, Cowellmedi Co., Pusan, Korea June-Sung Shim 10031947532846007580 10031947532846007580 No Department of Prosthodontics, College of Dentistry, Yonsei University, Seoul, Korea Chang-Mo Jeong 10031947532846007581 10031947532846007581 No Department of Prosthodontics, School of Dentistry, Pusan National University, Pusan, Korea Sang-Wan Shin 10031947532846007582 10031947532846007582 No Postgraduate School of Clinical Dentistry, Institute for Clinical Dental Research, Korea University, Seoul, Korea Jung-Bo Huh 10031947532846007583 10031947532846007583 Yes Department of Prosthodontics, School of Dentistry, Pusan National University, Pusan, Korea