fa Commercial mouthwashes are ineffective against oral MRSA biofilms بیماری های دهان Oral Medicine پژوهشي Research <p> <strong>Objective </strong></p><p> The aim of this study was to evaluate and compare the activity of oral mouthwashes against biofilm forms of MRSA isolated from the oral cavity and the bloodstream. </p><p> <strong>Study Design</strong></p><p>  The time-kill kinetics efficacy of 7 over-the-counter mouthwashes were tested against 28 clinical MRSA biofilm isolates for 0.5, 1 and 2 min. <strong></strong></p><p> <strong>Results</strong> </p><p> Treatments of MRSA biofilms formed by oral and bloodstream isolates were not significantly different, with mouthwashes displaying a rapid and modest anti-biofilm effect. None of the biofilm isolates were completely eradicated by the compounds tested, with a maximal killing of only approximately 70% shown by Corsodyl and Peroxyl. Maximum activity of all compounds tested was observed after 0.5 min. Fluorigard showed the poorest overall activity (57% reduction). </p><p> <strong>Conclusions</strong></p><p>  MRSA colonize the oral cavity, and are more prevalent in institutionalized persons and the elderly. Over-the-counter mouthwashes are ineffective at killing MRSA biofilms, which has infection control implications. </p><hr><p></p><p> <strong>Source: </strong>Oral Surgery, Oral Medicine, Oral Pathology, Oral Radiology </p><p> <a href="http://www.oooojournal.net/article/S2212-4403(12)01766-X/abstract" target="_blank"><font color="#0000ff">Full Text</font></a></p> 0 0 http://idai.ir/browse.php?a_code=A-10-32-1606&slc_lang=fa&sid=1 Karen Smith 10031947532846007448 10031947532846007448 No Institute of Healthcare Associated Infection, University of the West of Scotland, Ayr, UK Douglas P. Robertson 10031947532846007449 10031947532846007449 No Infection and Immunity Research Group, Glasgow Dental School, School of Medicine, College of Medical, Veterinary and Life Sciences, University of Glasgow, Glasgow, UK David F.Lappin 10031947532846007450 10031947532846007450 No Infection and Immunity Research Group, Glasgow Dental School, School of Medicine, College of Medical, Veterinary and Life Sciences, University of Glasgow, Glasgow, UK Gordon Ramage 10031947532846007451 10031947532846007451 Yes Infection and Immunity Research Group, Glasgow Dental School, School of Medicine, College of Medical, Veterinary and Life Sciences, University of Glasgow, Glasgow, UK