fa Efficacy of salvianolic acid B combined with triamcinolone acetonide in the treatment of oral submucous fibrosis بیماری های دهان Oral Medicine پژوهشي Research <p> <strong>Objective</strong></p><p>  The aim of this study was to investigate the effectiveness of triamcinolone acetonide (TA) and salvianolic acid B (SA-B) intralesional combined injection in the treatment of oral submucous fibrosis (OSF).</p><p> <strong> Material and Methods</strong> </p><p> A randomized clinical trial was performed. TA, SA-B, and TA combined with SA-B were consecutively applied intralesionally weekly for 20 weeks. Mouth opening and burning sensation improvement as determined by a 100-mm visual analog scale were evaluated at weeks 10, 20, and 44.</p><p> <strong> Results</strong></p><p>  Forty-two subjects fulfilled the study without obvious adverse reactions. The net gain in mouth opening was 2.00 ± 1.21 mm in the TA group, 3.48 ± 2.23 mm in the SA-B group, and 5.50 ± 1.80 mm in the TA + SA-B group at week 44. The burning sensation improved by 3.05 ± 0.76 in the TA group, 4.96 ± 0.97 in the SA-B group, and 6.11 ± 0.93 in the TA + SA-B group by the end of the study. <strong></strong></p><p> <strong>Conclusions</strong> </p><p> TA + SA-B intralesional injections improved mouth open and burning sensation in these OSF patients. </p><hr><p></p><p> <strong>Source: </strong>Oral Surgery, Oral Medicine, Oral Pathology, Oral Radiology </p><p> <a href="http://www.oooojournal.net/article/S2212-4403(12)01637-9/abstract" target="_blank"><font color="#0000ff">Full Text</font></a></p> 0 0 http://idai.ir/browse.php?a_code=A-10-32-1552&slc_lang=fa&sid=1 Xiao-Wen Jiang 10031947532846007158 10031947532846007158 Yes VDepartment of Stomatology, First People’s Hospital of Chenzhou, Chenzhou, Hunan, China Yi Zhang 10031947532846007159 10031947532846007159 No Department of Neurology, First People’s Hospital of Chenzhou, Chenzhou, Hunan, China Shou-kang Yang 10031947532846007160 10031947532846007160 No Department of Stomatology, First People’s Hospital of Chenzhou, Chenzhou, Hunan, China Hao Zhang 10031947532846007161 10031947532846007161 No Department of Stomatology, First People’s Hospital of Chenzhou, Chenzhou, Hunan, China Kun Lu 10031947532846007162 10031947532846007162 No Department of Stomatology, First People’s Hospital of Chenzhou, Chenzhou, Hunan, China Guo-Liang Sun 10031947532846007163 10031947532846007163 No Department of Stomatology, First People’s Hospital of Chenzhou, Chenzhou, Hunan, China