fa IgG4-related sclerosing disease clinically mimicking oral squamous cell carcinoma پاتولوزی دهان، فک و صورت Oral and Maxillofacial Pathology پژوهشي Research IgG4-related sclerosing disease is a distinct clinicopathologic entity known to involve the maxillofacial region, particularly the salivary, lacrimal, and pituitary glands. We report a case with lesions involving the tongue and palatine tonsil with associated skin lesions. A 45-year-old female patient presented with a history of soreness, dysphagia, and an asymptomatic rash involving the upper trunk. The initial clinical diagnosis of her oral lesions was squamous cell carcinoma. The diagnosis of an IgG4-related lesion was confirmed by histologic examination of the oral and skin lesions as well as confirmation of raised serum IgG4 levels. Tapering systemic corticosteroid therapy resulted in complete resolution of the lesions. This is the first report of IgG4-related sclerosing disease presenting as concurrent oral and skin lesions, with the oral lesion clinically resembling oral squamous cell carcinoma. Such lesions present a diagnostic challenge, but the outcome is very favorable. <hr><p> <strong>Source: </strong>Oral Surgery, Oral Medicine, Oral Pathology, Oral Radiology </p><p> <a href="http://www.oooojournal.net/article/S2212-4403(12)00353-7/abstract" target="_blank"><font color="#0000ff">Full Text</font></a></p> 0 0 http://idai.ir/browse.php?a_code=A-10-32-1534&slc_lang=fa&sid=1 Syed Ali Khurram 10031947532846007049 10031947532846007049 Yes Unit of Oral and Maxillofacial Pathology, School of Clinical Dentistry, University of Sheffield, Sheffield, United Kingdom Malee Fernando 10031947532846007050 10031947532846007050 No Department of Histopathology, Royal Hallamshire Hospital, Sheffield, United Kingdom Austen T.Smith 10031947532846007051 10031947532846007051 No Department of Oral and Maxillofacial Surgery, Sheffield and Barnsley Teaching Hospitals National Health Service Foundation Trust, Sheffield, United Kingdom Keith D.Hunter 10031947532846007052 10031947532846007052 No Unit of Oral and Maxillofacial Pathology, School of Clinical Dentistry, University of Sheffield, Sheffield, United Kingdom