en پریودنتولوژی Periodontology پژوهشي Research <p> <strong>Background:</strong> The objectives of this study are to compare differences in histologic and clinical healing following tooth extraction and ridge preservation using two different xenograft treatment protocols. </p><p> <strong>Methods:</strong> Forty-four patients with a non-molar tooth that required extraction and planned implant placement were randomly allocated into two ridge preservation protocol groups. Protocol 1 used a xenograft material consisting of 90% anorganic bovine bone in combination with 10% porcine collagen fibers combined with a resorbable bilayer membrane composed of non-cross-linked porcine types I and III collagen. Protocol 2 used a xenograft sponge composed of 70% cross-linked type I bovine collagen coated with a layer of non-sintered hydroxyapatite mineral on its surface combined with a resorbable membrane composed of type I porcine collagen cross-linked by natural ribose glycation. Following 21 weeks of healing, clinical measurements were repeated, and a core biopsy was obtained and prepared for histologic evaluation of percentages of vital bone, residual graft, and connective tissue/other (CT/other). </p><p> <strong>Results:</strong> Similar percentages of CT/other were detected between protocols, with no significant difference between groups (P = 0.763). A significantly greater percentage of vital bone was detected in specimens in protocol 2 (P <0.001). Protocol 1 presented with a mean of 32.83% ± 14.72% vital bone, 13.44% ± 11.57% residual graft material, and 53.73% ± 6.76% CT/other. Protocol 2 presented with a mean of 47.03% ± 9.09% vital bone, no detectable residual graft material, and 52.97% ± 9.09% CT/other. Clinically, no significant differences in dimensional changes were evident between ridge preservation protocols.</p><p> <strong> Conclusion</strong>: To the best of our knowledge, this study represents the first randomized controlled trial to evaluate clinical and histologic differences seen when using these two xenograft protocols for ridge preservation. </p><hr><p></p><p> <strong>Source: </strong>Journal of Periodentology </p><p> <a href="http://www.joponline.org/doi/abs/10.1902/jop.2012.120219" target="_blank"><font color="#0000ff">Full Text</font></a></p> Alveolar bone loss, bone resorption, dental implants, tooth extraction 0 0 http://idai.ir/browse.php?a_code=A-10-32-1289&slc_lang=en&sid=1 Deana Clare Cook 10031947532846005693 10031947532846005693 No Private practice, Wilmington, NC Brian L. Mealey mealey@uthscsa.edu 10031947532846005694 10031947532846005694 Yes Department of Periodontics, University of Texas Health Science Center at San Antonio, San Antonio, TX