en جراحی دهان، فک و صورت Oral and Maxillofacial Surgery پژوهشي Research <p> <strong>Background</strong>: Periodontitis is a disease that affects and destroys the tissues that support teeth. Tissue damage results from a prolonged inflammatory response to an ecological shift in the composition of subgingival biofilms. Three bacterial species that constitute the red complex group, Porphyromonas gingivalis, Tannerella forsythia, and Treponema denticola, are considered the main pathogens involved in periodontitis. <strong></strong></p><p> <strong>Materials and Methods</strong>: In the present study, a real‑time polymerase chain reaction bases assay was designed to detect and quantify red complex species, then used to investigate 307 periodontal pocket samples from 127 periodontitis patients and 180 controls.</p><p> <strong> Results</strong>: Significant higher prevalence of red complex species and increased amount of P. gingivalis and T. denticola were detected in periodontal pocket of periodontitis patients. </p><p> <strong>Conclusions:</strong> Results demonstrated that the test is a valuable tool to improve diagnosis of periodontal disease. </p><hr><p></p><p> <strong>Source: </strong>Dental Research Journal</p><p><a href="http://drj.mui.ac.ir/index.php/drj/article/view/1353" target="_blank"><font color="#0000ff"> Full Text</font></a></p> Bone, diseases, inflammation, ligament, periodontal, resorption, tooth 0 0 http://idai.ir/browse.php?a_code=A-10-32-1152&slc_lang=en&sid=1 Luca Scapoli 10031947532846005003 10031947532846005003 No Departments of Histology, Embryology and Applied Biology, Centre of Molecular Genetics, CARISBO Foundation, University of Bologna, Bologna Ambra Girardi 10031947532846005004 10031947532846005004 No Departments of Histology, Embryology and Applied Biology, Centre of Molecular Genetics, CARISBO Foundation, University of Bologna, Bologna Annalisa Palmieri 10031947532846005005 10031947532846005005 No Department of Medical-Surgical Sciences of Communication and Behavior, Section of Maxillofacial and Plastic Surgery, University of Ferrara,Ferrara Tiziano Testori 10031947532846005006 10031947532846005006 No Dentistry, Galeazzi Hospital, Milan, Italy Francesco Zuffetti 10031947532846005007 10031947532846005007 No Dentistry, Galeazzi Hospital, Milan, Italy Riccardo Monguzzi 10031947532846005008 10031947532846005008 No Private Practice, Dentist, Milan, Italy Dorina Lauritano 10031947532846005009 10031947532846005009 No Neurosciences and Biomedical Technologies, University,Milano Bicocca, Italy Francesco Carinci crc@unife.it 10031947532846005010 10031947532846005010 Yes Departments of Histology, Embryology and Applied Biology, Centre of Molecular Genetics, CARISBO Foundation, University of Bologna, Bologna