en پریودنتولوژی Periodontology پژوهشي Research <div><p dir="ltr" align="left"><strong>Background</strong></p><p dir="ltr">There is a great deal of studies on the relationship between the existence of <em>Helicobacter pylori </em>(<em>H. pylori</em>) in oral cavity (dental plaque) and in stomach of patients, with confl icting results worldwide. The purpose of this study was to systematically review the existing litreature to assess if the dental plaque could be a source of gastric <em>H. pylori </em>infection and to explore the source of heterogeneity around it.<br><strong>Methods</strong></p><p dir="ltr"><strong> </strong>We searched all the papers published since 2000 on international (Medline, ISI, Embase) databases using standard keywords. Two researchers evaluated the articles with standard critical appraisal form independently and those articles with the quality acquired greater than 70% were included in the study. The combined results were calculated with weighted average and the source of hetrogeneity was tested by meta-regression (random) model.<br><strong>Results</strong></p><p dir="ltr"><strong> </strong>Finally, 23 studies were included (1861 patients). The prevalence of co-infection of gastric and dental plaque <em>H. pylori </em>was 49.7% (95% CI 16–83.4%) and the percent of agreement between the dental plaque <em>H. pylori </em>status and the gastric <em>H. pylori </em>was estimated as 82%. Only one study has reported that dental treatment has a preventive effect on the recurrence of gastric <em>H. pylori </em>infection.<br><strong>Conclusion</strong></p><p dir="ltr"><strong> </strong>Co-infection of gastric <em>H. pylori </em>and dental plaque is reported by half of the studies. However, there is not enough evidence for the effi cacy of dental treatment on prevention of recurrent gastric <em>H. pylori </em>infection.<br></p><p dir="ltr" ><hr><p></p><p dir="ltr" align="left"><strong>Source:</strong> Dental Research Journal</p><p dir="ltr"><a href="http://www.drj.mui.ac.ir/index.php/drj/article/view/768" target="_blank"><font color="#0000cc">Full text</font></a></p></div> Helicobacter pylori, meta-analysis, systematic review 0 0 http://idai.ir/browse.php?a_code=A-10-32-84&slc_lang=en&sid=1 Nader Navabi 1003194753284600331 1003194753284600331 Yes Kerman University of Medical Science Moein Aramon 1003194753284600332 1003194753284600332 No Kerman University of Medical Science Ali Mirzazadeh 1003194753284600333 1003194753284600333 No Kerman University of Medical Sciences, Kerman, Iran