en ترمیمی Cosmetic and Restorative Dentistry پژوهشي Research <b> Clinical Relevance</b><div> Both the silorane and methacrylate resin systems showed good tissue compatibility, suggesting that their placement in contact with deep dentin in clinical procedures may be appropriate.</div><div><b> SUMMARY</b> </div><div><b>Objective:</b> This study evaluated, histopathologically, the pulpal and periapical response to a silorane-based resin (Filtek Silorane) and a methacrylate-based nanoparticle resin (Filtek Supreme XT) in deep cavities in dogs, having zinc oxide and eugenol-based cement (ZOE) as a control. </div><div>  <b>Methods:</b> The tooth/bone blocks were collected after 10 and 90 days and processed for microscopic analysis of the dentin, pulp, and periapical tissues using a score system. Data were analyzed statistically by Kruskal-Wallis and Dunn post-test (α=0.05). </div><div>  <b>Results:</b> At 10 days, the pulp, connective tissue, and periodontal ligament showed normal characteristics. No resorption areas were observed. Both resins caused significantly less (p<0.05) periapical and pulpal inflammatory response than ZOE. At 90 days, for all materials, the connective pulp tissue was healthy and dense, with a normal blood vessel system. The apical and periapical region had normal structure and thickness. </div><div>  <b>Conclusions:</b> The use of the Filtek Silorane and the Filtek Supreme XT resins caused no adverse pulpal and periapical reactions after restoration of deep dentin cavities in vivo.</div><hr><p class="MsoNormal" style="text-align: left direction: ltr unicode-bidi: embed"><b>Source: </b>Operative Dentistry <span style="font-size: 15.5pt line-height: 115% font-family: Verdana, sans-serif color: rgb(250, 250, 250) background-color: rgb(101, 111, 115) background-position: initial initial background-repeat: initial initial"><o:p /></span></p> <p class="MsoNormal" style="text-align: left direction: ltr unicode-bidi: embed"><a href="http://www.jopdentonline.org/doi/abs/10.2341/11-341-L" target="_blank"><font color="#0000ff">Full Text</font></a></p> 0 0 http://idai.ir/browse.php?a_code=A-10-32-981&slc_lang=en&sid=1 E Ruiz-de-Castañeda 10031947532846004265 10031947532846004265 No Academy of Medical Sciences and Health of Catalonia and Balears, Barcelona, Spain P Gatón-Hernández 10031947532846004266 10031947532846004266 No School of Dentistry, University of Barcelona, Barcelona, Spain EG Rodriguez 10031947532846004267 10031947532846004267 No School of Dentistry, University of Granada, Granada, Spain RAB Silva 10031947532846004268 10031947532846004268 No School of Dentistry of Ribeirão Preto, University of São Paulo, Department of Pediatric Clinic, Preventive and Community Dentistry, Ribeirão Preto, SP, Brazil P Nelson-Filho nelson@forp.usp.br 10031947532846004269 10031947532846004269 Yes School of Dentistry of Ribeirão Preto, University of São Paulo, Department of Pediatric Clinic, Preventive and Community Dentistry, Ribeirão Preto, SP, Brazil LAB Silva 10031947532846004270 10031947532846004270 No School of Dentistry of Ribeirão Preto, University of São Paulo, Department of Pediatric Clinic, Preventive and Community Dentistry, Ribeirão Preto, SP, Brazil