Evaluation of Meloxicam (A Cox-2 Inhibitor ) for management of Postoperative endodontic pain: A double-blind Placebo- controlled study
Dr. Nekoofar MH , Dr. Sadeghi panah M. , Dr. Dehpour AR. Successful management of endodontic pain represents a continuing challenge. The Purpose of this randomized, double-blind , placebo-controlled, parallel-group trial was to compare the pain reducing effect of oral preparations of meloxicam, piroxicam, and placebo in endodontic emergency patients. A total of 51 patients who presented to the Tehran University endodontic clinic and one private dental clinic were invited to participated. Patients were asked to evaluate their pretreatment pain with a visual-analog scale. After root canal therapy they were randomly assigned to one of three groups: meloxicam, piroxicam, or placebo. Each patient was sent home with a completion of therapy. The results of this study showed no significant differences between efficacy of meloxicam, piroxicam and placebo, but a significant effect of the time factor in reducing postoperative pain in all treatment group was observed.
Journal of Endodontics (2003, 29(10): 634) | 
