Objective:

  To evaluate the role of genetics and tooth wear in the etiology of dental crowding through the analysis of a split indigenous Amazon population.

 Materials and Methods:

  Dental crowding prevalence (n  =  117), tooth wear (n  =  117), and inbreeding coefficient (n  =  288) were compared for both villages. A biometric investigation was performed by dental cast analysis of 55 individuals with no tooth loss. Mann-Whitney statistics, independent t-tests, and Fisher exact tests were used at P < .05.

 Results:

  A high coefficient of inbreeding was confirmed in the resultant village (F  =  0.25, P < .001). Tooth wear was not significantly different (P  =  .99), while a significantly higher prevalence of dental crowding was confirmed in the original village (PR  =  6.67, P  =  0.02). Forty dental arches (n  =  20) were examined in the new group, and only one (2.5%) had a dental crowding ≥5 mm. In the original villages, we found 20 arches (28.6%) with dental crowding. No difference was observed for tooth size, while larger dental arch dimensions explained a lower level of dental crowding in the resultant village.

 Conclusions:

  Our findings downplay the widespread influence of tooth wear, a direct evidence of what an individual ate in the past, on dental crowding and emphasize the role of heredity, exacerbated through inbreeding, in the etiology of this malocclusion.

 Source: The Angel Orthodontists

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